Unlike traditional cannulae, Bi-Flow’s patented design incorporates a unique elbow and downstream perfusion channel. The cannula is easy to insert and remove and provides simultaneous systemic and distal perfusion to the lower limb.
Limb ischemia is a potentially life-threatening complication of femoral artery cannulation. It can affect between 10% and 70% of patients undergoing VA-ECMO and may have devastating consequences such as higher mortality, higher morbidity and longer hospital stay.
The LivaNova Bi-Flow cannula is designed to reduce this risk in all procedures requiring femoral cannulation. In addition to its unique bidirectional perfusion design, Bi-Flow also offers:
- Simple and straightforward insertion and removal process, both percutaneously using a standard needle and guide wire technique or after a surgical cut-down
- DOP-free tubing and Ph.I.S.I.O. coating for enhanced biocompatibility
- Optimal pressure drop level for adequate systemic perfusion
- Unique fixation device designed to ensure that it remains correctly positioned during the procedure
In addition to the ECMO version, Bi-Flow is approved also for cardiopulmonary bypass procedures for periods up to 6-hours, to deliver its benefits to patients undergoing complex cardiac surgery procedures and requiring femoral cannulation.
 Bonicolini et al. Limb ischemia in peripheral veno-arterial extracorporeal membrane oxygenation: a narrative review of incidence, prevention, monitoring, and treatment. Critical Care (2019) 23:266
 Marasco et al. Innovations (Phila). 2018 Mar/Apr;13(2):97-103